Umuti w'amatungo uvura indwara ya Colistin Sulfate CAS 1264-72-8

Ibisobanuro by'igicuruzwa

Ifite ingaruka zikomeye ku mikorobe za garama-negative, kandi bagiteri zoroshye zirimo Pseudomonas aeruginosa, Escherichia coli, Enterobacteria, Klebsiella, Salmonella, Shigella, Pasteurella na Vibrio. Proteus, Brucella, Serratia na bagiteri zose za garama-negative zari zihanganye n'iki gicuruzwa.Colistin SulfateKu miti yica udukoko buhoro buhoro, uruhare runini mu ngirabuzimafatizo za bagiteri, iyo ihuye na bagiteri zishobora kwibasirwa n’uturemangingo, imiterere yayo ya amino yigenga (Yang) na fosfeti ester y’umuzi wa aside fosforike ku ngirabuzimafatizo za bagiteri (hamwe n’ingufu zikoreshwa mu gupima amashanyarazi), byongera ubushobozi bwo kwinjira mu ngirabuzimafatizo, bigatera uturemangingo tw’ibintu by’ingenzi nka aside amine, Piao songs, pyrimidine, K + byayo.

Agukoresha

Ikoreshwa cyane cyane mu kuvura indwara zo mu mara ziterwa na bacilli ya Grame-negative (Escherichia coli, nibindi). Ifite akamaro kandi mu kurwanya Pseudomonas aeruginosa (sepsis, indwara zo mu nzira y'inkari, ubushye cyangwa indwara zikomeretsa).

Ibiranga

(1) Ifite ubudahangarwa bukomeye cyane kuri bagiteri za Gram negative. Cyane cyane, ifite ingaruka zihariye ku mikurire ya Escherichia coli, Salmonella, na Pseudomonas aeruginosa.

(2) Igira ingaruka mbi ku mikorobe. Mu kubangamira imikorere y’uturemangingo tw’umubiri, bagiteri zirapfa.

(3) Nta kibazo na kimwe kigaragara ku bijyanye no kudakira imiti. Nta kudakira kwa R-factor kwabonetse.

(4) Ikorana neza n'imiti irwanya bagiteri za Gram. Iyo ihujwe na zinc bacitracin, flavomycin, sulfonamides, semi synthetic penicillin, gentamicin, n'ibindi, ingaruka ziba nziza kurushaho.

(5) Nta bisigazwa. Iyo binyowe, hafi ya byose ntibinjira mu mara, ariko mu gihe cyo guterwa mu mitsi, gukusanya no kwinjiza amaraso biba byiza, bityo nta mpamvu yo guhangayikishwa n'ibisigazwa biri mu bikomoka ku matungo.

(6) Guteza imbere ubworozi n'inkoko, no gukumira no kurwanya indwara yandura mu matungo n'inkoko.