Abashakashatsi bavumbuye uburyo ibimera bigenzura poroteyine za DELLA

Abashakashatsi bo mu Ishami rya Biochimie mu Kigo cy’Ubumenyi bw’Abahinde (IISc) bavumbuye uburyo bwari bumaze igihe bushakishwa bwo kugenzura imikurire y’ibimera byo ku butaka bya kera nka bryophytes (itsinda ririmo mosses na liverworts) byagumanye mu bimera byaje kurabya nyuma.
Ubushakashatsi bwasohotse mu kinyamakuru Nature Chemical Biology, bwibanze ku kugenzura poroteyine za DELLA, ikigo cy’ingenzi gishinzwe gukura kw’uturemangingo, kigabanya igabanyuka ry’uturemangingo mu turemangingo tw’inda (embryophytes).
Igishimishije ni uko bryophytes, ibimera bya mbere byagaragaye ku butaka mu myaka igera kuri miliyoni 500 ishize, bibura receptor ya GID1 nubwo byakoraga phytohormone GA. Ibi bitera kwibaza uburyo imikurire n'iterambere ry'ibi bimera byo ku butaka bya mbere byagenzurwaga.
Bakoresheje liverwort Marchantia polymorpha nk'icyitegererezo cy'uburyo, abashakashatsi basanze ibi bimera bya kera bikoresha enzyme yihariye, MpVIH, ikora inositol pyrophosphate (InsP₈), ituma bishobora gusenya DELLA bitabaye ngombwa aside gibberellic.
Abashakashatsi basanze DELLA ari imwe mu ntego z'uturemangingo twa VIH kinase. Byongeye kandi, babonye ko ibimera bidafite MpVIH bisa n'imiterere y'ibimera bya M. polymorpha bikura cyane DELLA.
“Kuri iyi ngingo, twari twishimiye gusobanukirwa niba ubushobozi bwa DELLA cyangwa ibikorwa byayo byiyongera mu bimera bidafite ubushobozi bwa MpVIH,” ibi byavuzwe na Priyanshi Rana, umwanditsi wa mbere akaba n'umunyeshuri warangije mu itsinda ry'ubushakashatsi rya Lahey. Dukurikije igitekerezo cyabo, abashakashatsi basanze gukumira DELLA byakuyeho cyane imiterere mibi y'imikurire n'imikurire y'ibimera bya MpVIH bitameze neza. Ibi byavuye mu bushakashatsi bigaragaza ko VIH kinase igenga nabi DELLA, bityo igateza imbere imikurire n'imikurire y'ibimera.
Ubushakashatsi kuri poroteyine za DELLA bwatangiye kuva mu gihe cy’impinduramatwara y’ibidukikije, ubwo abahanga mu bya siyansi bakoreshaga ubushobozi bwabo batabizi kugira ngo bateze imbere ubwoko bw’ibimera bitanga umusaruro mwinshi. Nubwo uburyo bwazo bwakoraga butari busobanutse neza icyo gihe, ikoranabuhanga rigezweho ryemerera abahanga mu bya siyansi guhindura imikorere y’izo poroteyine binyuze mu buhanga mu by’uturemangingo, bigatuma umusaruro w’ibihingwa wiyongera neza.
Kwiga ibimera byo ku butaka bya kera bitanga kandi ubumenyi ku mihindukire yabyo mu myaka miliyoni 500 ishize. Urugero, nubwo ibimera bigezweho by'indabyo bihungabanya poroteyine za DELLA binyuze mu buryo bushingiye kuri aside ya gibberellic, ahantu hahuza InsP₈ harabikwa. Ibi bivumbuye bitanga ubumenyi ku mihindukire y'inzira z'uturemangingo uko igihe kigenda gihita.
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