Guhura n’imiti imwe n'imwe yica udukoko, urugero nk'umuti wica imibu, bifitanye isano n'ingaruka mbi ku buzima, nk'uko isesengura ry’ubushakashatsi bwakozwe na leta zunze ubumwe.
Mu bitabiriye ubushakashatsi bw’ibizamini by’ubuzima n’imirire (NHANES), urwego rwo hejuru rw’imiti yica udukoko twangiza udukoko twitwa pyrethroide yo mu rugo rwahujwe n’ibyago bitatu by’impfu z’indwara zifata umutima (igipimo cya 3.00, 95% CI 1.02–8.80) Dr. Wei Bao na bagenzi be bo muri kaminuza ya Iowa muri raporo y'Umujyi wa Iowa.
Abantu bari murwego rwo hejuru bahura niyi miti yica udukoko nabo bafite ibyago 56% byimpfu ziterwa nimpamvu zose ugereranije nabantu bari murwego rwo hasi rwo kwanduza iyi miti yica udukoko (RR 1.56, 95% CI 1.08-22. 26).
Icyakora, abanditsi bavuze ko imiti yica udukoko twa pyrethroide itajyanye n’impfu za kanseri (RR 0,91, 95% CI 0.31-22.72).
Abanyamideli bahinduwe kubwoko / ubwoko, igitsina, imyaka, BMI, creatinine, indyo, imibereho, hamwe na sociodemografiya.
Imiti yica udukoko twa Pyrethroid yemerewe gukoreshwa n’ikigo cyo muri Amerika gishinzwe kurengera ibidukikije kandi ikoreshwa cyane mu kurwanya imibu, imiti yica imitwe, shampo y’amatungo hamwe n’ibiti, hamwe n’ibindi bicuruzwa byangiza udukoko two mu ngo no hanze kandi bifatwa nk’umutekano muke.
Itsinda rya Bao ryasobanuye riti: “Nubwo hakozwe pyrethroide zirenga 1.000, ku isoko ryo muri Amerika hari imiti yica udukoko twitwa pyrethroide igera ku icumi gusa nka permethrine, cypermethrin, deltamethrin na cyfluthrin.” Yongeyeho ko ikoreshwa rya pyrethroide “ryiyongereye.”Ati: “Mu myaka ya vuba aha, ibintu byarushijeho kuba bibi bitewe no guta buhoro buhoro ikoreshwa rya organofosifati mu mazu atuyemo.“
Mu bisobanuro biherekeje, Stephen Stellman, impamyabumenyi y'ikirenga, MPH, na Jean Mager Stellman, impamyabumenyi y'ikirenga ya kaminuza ya Columbia i New York, menya ko pyrethroide “ari yo ya kabiri yica udukoko twangiza udukoko ku isi, yose hamwe akaba ibihumbi. kilo na miliyoni magana z'amadorari y'Abanyamerika. ”Igurishwa ry’Amerika mu madorari y'Abanyamerika.“
Byongeye kandi, baranditse bati: "Imiti yica udukoko twitwa pyrethroid irahari hose kandi byanze bikunze guhura nabyo."Stelmans yagize ati: "Ntabwo ari ikibazo gusa ku bakora mu buhinzi:" Gutera imibu yo mu kirere kugira ngo igabanye virusi ya West Nile n'izindi ndwara ziterwa na virusi i New York n'ahandi hose zishingiye cyane kuri pyrethroide. "
Ubushakashatsi bwasuzumye ibyavuye mu bantu barenga 2000 bitabiriye umushinga wa NHANES 1999-222 bapimwe umubiri, bakusanya amaraso, kandi basubiza ibibazo by’ubushakashatsi.Indwara ya Pyrethroid yapimwe nurwego rwinkari za aside-fenoxybenzoic 3, metabolite ya pyrethroid, abayitabiriye bagabanijwemo tertile yo guhura.
Mu gihe cyo gukurikirana imyaka 14, abitabiriye 246 bapfuye: 52 bazize kanseri na 41 bazize indwara z'umutima.
Ugereranije, abirabura batari Hisipaniya bahuye cyane na pyrethroide kurusha Abahasipanyika n'abazungu batari Hisipaniya.Abantu bafite amikoro make, urwego rwo hasi rwuburezi, hamwe nubuziranenge bwimirire mibi nabo bakunze kugira tertile nyinshi yo guhura na pyrethroid.
Stellman na Stellman bagaragaje "ubuzima bucye cyane" bwa biomarkers ya pyrethroid, ugereranije amasaha 5.7 gusa.
Bagize bati: "Kuba hari urwego rushobora gukurwaho metabolite ya pyrethroide ikuweho vuba mu bantu benshi, batandukanye mu turere dutandukanye byerekana ko abantu bamara igihe kirekire kandi binagaragaza akamaro ko kumenya ibidukikije."
Icyakora, bavuze kandi ko kubera ko abitabiriye ubushakashatsi bari bakiri bato mu myaka (20 kugeza 59), biragoye kugereranya neza ubunini bw’ishyirahamwe n’impfu zifata umutima.
Stellman na Stellman bavuze ko ariko, “igipimo cy’ibiza kidasanzwe” gisaba ubushakashatsi bwinshi kuri iyi miti ndetse n’ingaruka zishobora guteza ubuzima rusange.
Indi mbogamizi y’ubushakashatsi, nk’uko abanditsi babivuga, ni ugukoresha urugero rw’inkari zo mu murima kugira ngo bapime metabolite ya pyrethide, idashobora kwerekana impinduka uko ibihe bigenda bisimburana, bigatuma habaho kwibeshya ku buryo busanzwe bwo kwanduza imiti yica udukoko twa pyrethide.
Kristen Monaco numwanditsi mukuru winzobere muri endocrinology, psychiatry namakuru ya neprologiya.Afite icyicaro i New York kandi yabanye na sosiyete kuva mu 2015.
Ubushakashatsi bwatewe inkunga n’ikigo cy’igihugu cy’ubuzima (NIH) binyuze mu kigo cy’ubushakashatsi ku buzima bushingiye ku bidukikije muri kaminuza ya Iowa.
Igihe cyo kohereza: Nzeri-26-2023