Florfenicolni antibiyotike yagutse, ifite ingaruka nziza zo guhagarika bagiteri nziza na bagiteri mbi.Kubwibyo, ubworozi bwinshi bwingurube bukunze gukoresha florfenicol kugirango wirinde cyangwa uvure ingurube mugihe cyindwara zikunze kubaho.abarwayi.Abakozi b'amatungo bo mu bworozi bw'ingurube bakoresha super-dose ya florfenicol mu kuvura cyangwa gukumira indwara batitaye ku ndwara, batitaye ku itsinda cyangwa icyiciro.Florfenicol ntabwo ari umuti, kandi igomba gukoreshwa neza kugirango igere ku ngaruka zifuzwa.Hano hepfo turamenyekanisha imyumvire isanzwe yo gukoresha florfenicol muburyo burambuye, twizeye ko izafasha benshi mubahinzi b'ingurube:
1. Indwara ya Antibacterial yaflorfenicol
1. Ifite antibacterial nini cyane, kandi igira ingaruka zikomeye zo kwica kuri bagiteri-nziza ya bagiteri na bagiteri mbi, hamwe na anaerobic Gram-positif na bagiteri mbi, rickettsia, amibe, nibindi. Ingaruka zikomeye za antibacterial.
2. Muri vitro no muri vivo ubushakashatsi bwerekana ko ibikorwa bya antibacterial ari byiza cyane kuruta imiti ya antibacterial.
3. Gukora vuba, florfenicol irashobora kugera kumiti ivura mumaraso nyuma yisaha 1 nyuma yo guterwa inshinge, kandi ibiyobyabwenge bishobora kugerwaho mumasaha 1.5-3;kumara igihe kinini, ibiyobyabwenge byamaraso bishobora gukomeza amasaha arenga 20 nyuma yubuyobozi bumwe.
4. Irashobora kwinjira mu nzitizi y'amaraso n'ubwonko, kandi ingaruka zayo zo kuvura indwara ya bagiteri ya meningite ntagereranywa n'indi miti igabanya ubukana.
5. Ntabwo ifite uburozi n'ingaruka iyo ikoreshejwe mubisabwa, itsinze akaga ko kubura amaraso make nubundi burozi buterwa na thiamphenicol, kandi ntibitera kwangiza inyamaswa nibiryo.Ikoreshwa mu kwanduza ibice bitandukanye byumubiri biterwa na bagiteri mu nyamaswa.Kuvura, harimo gukumira no kuvura indwara z’ubuhumekero za bagiteri, meningite, pleurisy, mastitis, indwara zo mu nda na syndrome ya nyuma y’ingurube.
2. Indwara ya bagiteri yanduye yaflorfenicol
1. Indwara z'ingurube aho florfenicol ikundwa
Iki gicuruzwa kirasabwa nk'umuti uhitamo umusonga w'ingurube, porcine yanduye pleuropneumonia n'indwara ya Haemophilus parasuis, cyane cyane mu kuvura bagiteri zirwanya fluoroquinolone n'izindi antibiyotike.
2. Florfenicol irashobora kandi gukoreshwa mukuvura indwara zingurube zikurikira
Irashobora kandi gukoreshwa mu kuvura indwara z'ubuhumekero ziterwa na Streptococcus zitandukanye (pneumoniya), Bordetella bronchiseptica (rinite atrophique), Mycoplasma pneumoniae (asima y'ingurube), n'ibindi.;salmonellose (piglet paratyphoid), colibacillose (asima y'ingurube) Indwara zifata igifu nka enterite iterwa n'impiswi z'umuhondo, impiswi zera, indwara y'ingurube) n'izindi bagiteri zoroshye.Florfenicol irashobora gukoreshwa mu kuvura izo ndwara z'ingurube, ariko ntabwo ariwo muti uhitamo izo ndwara z'ingurube, bityo ugomba gukoreshwa witonze.
3. Gukoresha nabiflorfenicol
1. Igipimo ni kinini cyane cyangwa gito.Ingano nini ni uburozi, kandi dosiye ntoya ntacyo ikora.
2. igihe ni kirekire cyane.Bimwe murigihe kirekire gukoresha ibiyobyabwenge byinshi nta kubuza.
3.koresha ibintu, amakosa yo murwego.Kubiba inda n'ingurube zibyibushye zikoresha ibiyobyabwenge mu buryo butarobanuye, bigatera uburozi cyangwa ibisigazwa byibiyobyabwenge, bikavamo umusaruro muke ndetse nibiribwa.
4. Guhuza bidakwiye.Abantu bamwe bakunze gukoresha florfenicol hamwe na sulfonamide na cephalosporine.Niba ari siyanse kandi yumvikana birakwiye gushakisha.
5. Kugaburira kuvanze ntibivanze neza, bikavamo nta ngaruka zibiyobyabwenge cyangwa uburozi.
Icya kane, ikoreshwa ryaflorfenicolkwirinda
1. Iki gicuruzwa ntigikwiye gukoreshwa hamwe na macrolide, lincosamide na diterpenoid igice cya sintetike ya antibiotike - Tiamuline, ishobora gutanga ingaruka mbi iyo ikoreshejwe hamwe.
2. Iki gicuruzwa ntigishobora gukoreshwa hamweβ-lactone amine na fluoroquinolone, kubera ko iki gicuruzwa nikintu cyihuta cya bacteriostatike ikingira intungamubiri za poroteyine, kandi icya nyuma ni bagiteri yihuta cyane mugihe cyimyororokere.Mubikorwa byabanje, synthesis ya bagiteri ya protein ihagarikwa byihuse, bagiteri ihagarika gukura no kugwira, kandi ingaruka za bagiteri ziterwa na nyuma ziracika intege.Kubwibyo, mugihe ubuvuzi bukeneye kugira ingaruka zihuse zo kuboneza urubyaro, ntibushobora gukoreshwa hamwe.
3. Iki gicuruzwa ntigishobora kuvangwa na sodium ya sulfadiazine yo gutera inshinge.Ntigomba gukoreshwa ifatanije nibiyobyabwenge bya alkaline mugihe itanzwe kumunwa cyangwa mumitsi, kugirango wirinde kubora no gutsindwa.Ntibikwiye kandi gutera inshinge hamwe na tetracycline hydrochloride, kanamycin, adenosine triphosphate, coenzyme A, nibindi, kugirango wirinde kugwa no kugabanuka kwingirakamaro.
4. Kwangirika kw'imitsi na necrosis birashobora guterwa nyuma yo gutera inshinge.Kubwibyo, irashobora guterwa ubundi buryo mumitsi yimbitse yijosi nigituba, kandi ntabwo ari byiza gusubiramo inshinge kurubuga rumwe.
5. Kubera ko iki gicuruzwa gishobora kuba gifite intanga ngore, kigomba gukoreshwa ubwitonzi mu mbuto zitwite kandi zonsa.
6. Iyo ubushyuhe bwumubiri wingurube zirwaye buri hejuru, burashobora gukoreshwa hamwe na antipyretic analgesics na dexamethasone, kandi ingaruka nibyiza.
7. Mu gukumira no kuvura indwara y’ubuhumekero ya porcine (PRDC), abantu bamwe basaba guhuza florfenicol na amoxicillin, florfenicol na tylosine, na florfenicol na tylosine, bidakwiye., kubera ko ukurikije ibya farumasi, byombi ntibishobora gukoreshwa hamwe.Nyamara, florfenicol irashobora gukoreshwa hamwe na tetracycline nka doxycycline.
8. Iki gicuruzwa gifite uburozi bwa hematologiya.Nubwo bitazatera amagufa adasubirwaho marrow aplastique anemia, ihindagurika rya erythropoiesis iterwa nayo irasanzwe kuruta chloramphenicol (ubumuga).Yandujwe mugihe cyo gukingira cyangwa inyamaswa zifite ubudahangarwa bukabije.
9. Gukoresha igihe kirekire birashobora gutera ikibazo cyigifu no kubura vitamine cyangwa ibimenyetso bya superinfection.
10. Mu gukumira no kuvura indwara z’ingurube, hakwiye kwitabwaho, kandi imiti igomba gutangwa hakurikijwe igipimo cyagenwe n’ubuvuzi, kandi ntigomba gukoreshwa nabi kugirango birinde ingaruka mbi.
11. Ku nyamaswa zidafite impyiko, igipimo kigomba kugabanuka cyangwa intera yubuyobozi igomba kongerwa.
12. Mugihe cy'ubushyuhe buke, usanga igipimo cyo gusesa gitinda;cyangwa igisubizo cyateguwe gifite imvura ya florfenicol, gushyushya gake (ntibirenze 45℃), byose birashobora guseswa vuba.Igisubizo cyateguwe gikoreshwa neza mumasaha 48.
Ni byiza cyane gukoresha ifishi ikwiye ukurikije intangiriro yavuzwe haruguru hanyuma ukareba dosiye isabwa.Inyamaswa ku giti cye zishobora gutakaza ubushake bwo kurya, kugabanuka gufata amazi cyangwa impiswi, ububabare buke aho batewe inshinge ndetse nuduce duto duto, ibyo byose nibisanzwe kandi bigasubira mubisanzwe nyuma yo guhagarika ibiyobyabwenge.
Igihe cyo kohereza: Werurwe-28-2022